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临床试验/NCT02054767
NCT02054767已完成4 期

Anesthetic Efficacy of Articaine, Lidocaine and Mepivacaine in Patients With Irreversible Pulpitis of Mandibular Molar

University of Sao Paulo2 个研究点 分布在 1 个国家目标入组 66 人开始时间: 2010年8月最近更新:
适应症
相关药物

试验速览

阶段
4 期
状态
已完成
入组人数
66
试验地点
2
主要终点
pulpal anesthesia

研究概览

简要总结

The purpose of this study was to compare the anesthetic efficacy of articaine, lidocaine and mepivacaine in patients with irreversible pulpitis of mandibular molar.

详细描述

Conventional inferior alveolar nerve block (IANB) is the most commonly used technique for achieving pulpal anesthesia in posterior mandibular endodontic procedures. However, IANB has a high failure rate and success rates are even lower when applied for the treatment of mandibular posterior teeth with irreversible pulpitis.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • clinical diagnosis of irreversible pulpitis
  • good health
  • had at least 1 adjacent tooth plus a healthy canine

排除标准

  • took medication could be interacting with any of the anesthetics used

结局指标

主要结局

pulpal anesthesia

时间窗: Ten minutes after the inferior alveolar nerve block

pulpal anesthesia was tested with an electric pulp stimulator

次要结局

  • analgesia(the patients were instructed to report any painful sensation at three phases: 1) dentin 2) pulp chamber 3) root canal)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Isabel Peixoto Tortamano

PhD

University of Sao Paulo

研究点 (2)

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