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Postoperatieve pijnbehandeling middels continue epidurale toediening van bupivacaïne/sufentanil versus bupivacaïne/morfine bij patiënten na een grote chirurgische ingreep.

Recruiting
Conditions
epidural, bupivacaïne, sufentanil, morphine, analgesia, side effectsEpiduraal, morfine, analgesie, bijwerkingen
Registration Number
NL-OMON22506
Lead Sponsor
MC
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
424
Inclusion Criteria

1. Age 18 years or older;

2. Scheduled major surgery;

Exclusion Criteria

1. Patients with an allergy to one of the study medications;

2. Patients using opioids pre-operatively;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The pain scores during the first 72 hours after surgery.
Secondary Outcome Measures
NameTimeMethod
The quality of pain relief (as experienced by the patient) and side/adverse effects: pruritis, drowsiness, nausea, vomiting and/or motor block, sedation, respiratory depression and episodes of hypotension.
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