Psychodynamic Internet Treatment Versus Cognitive Behavioral Therapy (CBT) for Generalized Anxiety Disorder

Not Applicable

Completed

• Conditions: Generalized Anxiety Disorder
• Interventions: Behavioral: iCBT; Behavioral: iPDT

• Registration Number: NCT01312116
• Lead Sponsor: Linkoeping University

Brief Summary

The objective is to test if Internet-delivered cognitive behavior therapy (iCBT) or Internet-delivered psychodynamic therapy (iPDT) performs better for a population with generalized anxiety disorder (GAD), compared to a wait-list control condition.

Detailed Description

This was a non-inferiority trial within the context of a parallel group study with unrestricted randomisation in 1:1:1 ratio conducted in Sweden. Outcome assessors were blind to treatment status.

Study Timeline

• Study Start: 2009-01
• Primary Completion: 2009-10
• Study Completion: 2010-12
• Status Verified: 2011-03
• Study First Submitted: 2011-03-07
• Study First Submitted QC: 2011-03-09
• Last Update Submitted: 2011-03-09
• Study First Posted: 2011-03-10
• Last Update Posted: 2011-03-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 81

Inclusion Criteria

• fulfill the diagnostic criteria for GAD according to DSM-IV
• have access to the Internet
• have good knowledge of the Swedish language

Exclusion Criteria

• recent (during last 6 weeks) change in psychiatric medication
• presently in any other psychological treatment
• severe depression
• suicidal ideation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Internet-delivered CBT	iCBT	Active treatment: Internet-delivered Cognitive Behavior Therapy, 8 weeks treatment, guided self-help
Internet-delivered PDT	iPDT	Active treatment: Internet-delivered Psychodynamic Therapy Active treatment: Internet-delivered Psychodynamic Therapy, 8 weeks treatment, guided self-help

Primary Outcome Measures

Name	Time	Method
Penn State Worry Questionnaire (PSWQ)	Two weeks pre treatment to two weeks post treatment.	Change from baseline in anxiety symptoms to two weeks post treatment.

Secondary Outcome Measures

Name	Time	Method
Montgomery Åsberg Depression Rating Scale-Self Rated (MADRS-S)	Two weeks pre treatment to two weeks post treatment	Change from baseline in depressive symptoms to two weeks post treatment.
Quality of Life Inventory (QOLI)	Two weeks pre treatment to two weeks post treatment	Change from baseline in quality of life status to two weeks post treatment.
Beck Depression Inventory (BDI)	Two weeks pre treatment to two weeks post treatment	Change from baseline in depressive symptoms to two weeks post treatment.
Beck Anxiety Inventory (BAI)	Two weeks pre treatment to two weeks post treatment	Change from baseline in anxiety symptoms to two weeks post treatment.
Trimbos and iMTA questionnaire on Costs associated with Psychiatric illness (TIC-P)	Two weeks pre treatment to two weeks post treatment	Change from baseline in societal cost of illness to two weeks post treatment.
State Trait Anxiety Inventory (STAI)	Two weeks pre treatment to two weeks post treatment	Change from baseline in anxiety symptoms to two weeks post treatment.
Generalized Anxiety Disorder Questionnaire IV (GAD-Q IV)	Two weeks pre treatment to two weeks post treatment	Change from baseline in anxiety symptoms to two weeks post treatment.

Trial Locations

Locations (1)

Linköping University; 🇸🇪 Linköping, Östergötland, Sweden