Impact of Long Distance Mountain Race on Knee Cartilage.

Completed

• Conditions: Sports Medicine
• Interventions: Other: Long-distance mountain running

• Registration Number: NCT04545216
• Lead Sponsor: University Hospital, Grenoble

Brief Summary

Long-distance mountain running is increasingly popular among European and North America countries. Long-distance races are organized in various mountains and can reach up to 160 km (100 miles) with several thousands meters of climbing. The pathophysiological consequences of such extreme effort is still a matter a debate. From a muskelo-skeletal perspectives, the potential lower-limb join damage is a major health issue. The present study aims to use objective magnetic resonance imaging (MRI) techniques to describe the consequences of performing long-distance mountain running races on the knee cartilage.

Detailed Description

Healthy male runners will perform T2 MRI knee cartilage examination before, immediatly after and 1 month after 3 distinct long-distance mountain races of 40, 55 and 160 km. The physiological responses during the races (speed, heart rate, glycemia) will also be recordered.

Study Timeline

• Study Start: 2020-09-03
• Study First Submitted: 2020-09-03
• Study First Submitted QC: 2020-09-03
• Study First Posted: 2020-09-10
• Primary Completion: 2021-08-31
• Study Completion: 2021-12-31
• Status Verified: 2022-03
• Last Update Submitted: 2022-03-25
• Last Update Posted: 2022-03-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 54

Inclusion Criteria

• no cardiac, respiratory or neuromuscular diseases
• more than 2 years of experience in mountain race
• no contre-indication for participating in a mountain race

Exclusion Criteria

• history of knee surgery
• contre-indication to MRI

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
UTV 55	Long-distance mountain running	athletes participating to the 55 km mountain race.
UT4M 40	Long-distance mountain running	athletes participating to the 40 km mountain race.
UT4M 160	Long-distance mountain running	athletes participating to the 160 km mountain race.

Primary Outcome Measures

Name	Time	Method
T2 MRI	from before to immediatly after the long-distance race	Change in T2 relaxation time of the knee cartilage

Secondary Outcome Measures

Name	Time	Method
Heart rate	Continuous measurement during the race	Mean heart rate during the race
Glycemia	Continuous measurement during the race	Mean glycemia during the race

Trial Locations

Locations (1)

Doutreleau; 🇫🇷 Grenoble, France