Assessment of the Impact of an Ultratrail on the Knee Cartilage by Using T2 MRI: a Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 54
- 试验地点
- 1
- 主要终点
- T2 MRI
研究概览
简要总结
Long-distance mountain running is increasingly popular among European and North America countries. Long-distance races are organized in various mountains and can reach up to 160 km (100 miles) with several thousands meters of climbing. The pathophysiological consequences of such extreme effort is still a matter a debate. From a muskelo-skeletal perspectives, the potential lower-limb join damage is a major health issue. The present study aims to use objective magnetic resonance imaging (MRI) techniques to describe the consequences of performing long-distance mountain running races on the knee cartilage.
详细描述
Healthy male runners will perform T2 MRI knee cartilage examination before, immediatly after and 1 month after 3 distinct long-distance mountain races of 40, 55 and 160 km. The physiological responses during the races (speed, heart rate, glycemia) will also be recordered.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years(Adult)
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •no cardiac, respiratory or neuromuscular diseases
- •more than 2 years of experience in mountain race
- •no contre-indication for participating in a mountain race
排除标准
- •history of knee surgery
- •contre-indication to MRI
结局指标
主要结局
T2 MRI
时间窗: from before to immediatly after the long-distance race
Change in T2 relaxation time of the knee cartilage
次要结局
- Heart rate(Continuous measurement during the race)
- Glycemia(Continuous measurement during the race)
