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临床试验/NCT04545216
NCT04545216已完成不适用

Assessment of the Impact of an Ultratrail on the Knee Cartilage by Using T2 MRI: a Pilot Study

University Hospital, Grenoble1 个研究点 分布在 1 个国家目标入组 54 人开始时间: 2020年9月3日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
54
试验地点
1
主要终点
T2 MRI

研究概览

简要总结

Long-distance mountain running is increasingly popular among European and North America countries. Long-distance races are organized in various mountains and can reach up to 160 km (100 miles) with several thousands meters of climbing. The pathophysiological consequences of such extreme effort is still a matter a debate. From a muskelo-skeletal perspectives, the potential lower-limb join damage is a major health issue. The present study aims to use objective magnetic resonance imaging (MRI) techniques to describe the consequences of performing long-distance mountain running races on the knee cartilage.

详细描述

Healthy male runners will perform T2 MRI knee cartilage examination before, immediatly after and 1 month after 3 distinct long-distance mountain races of 40, 55 and 160 km. The physiological responses during the races (speed, heart rate, glycemia) will also be recordered.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • no cardiac, respiratory or neuromuscular diseases
  • more than 2 years of experience in mountain race
  • no contre-indication for participating in a mountain race

排除标准

  • history of knee surgery
  • contre-indication to MRI

结局指标

主要结局

T2 MRI

时间窗: from before to immediatly after the long-distance race

Change in T2 relaxation time of the knee cartilage

次要结局

  • Heart rate(Continuous measurement during the race)
  • Glycemia(Continuous measurement during the race)

研究者

发起方
University Hospital, Grenoble
申办方类型
Other
责任方
Sponsor

研究点 (1)

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