Sleep disruption in quadriplegia – A pilot study exploring whether 3mg melatonin induces sleep
Phase 4
Completed
- Conditions
- nrefreshing sleepUnrefreshing sleepRespiratory - Other respiratory disorders / diseases
- Registration Number
- ACTRN12608000504314
- Lead Sponsor
- Austin Health
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 5
Inclusion Criteria
Complete (motor and sensory) quadriplegia (T1 or higher lesion)
Exclusion Criteria
Major psychological or psychiatric disturbances, Neurological damage other than spinal cord injury, Other significant co-morbidity, Beta blockers.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How does melatonin modulate sleep architecture in complete quadriplegia via MT1/MT2 receptor pathways?
What comparative effectiveness data exist for melatonin vs. standard hypnotics in spinal cord injury patients with unrefreshing sleep?
Which circadian rhythm biomarkers predict melatonin response in quadriplegia-associated sleep disorders?
What adverse event profiles are reported for melatonin in patients with respiratory comorbidities and spinal trauma?
Are there synergistic effects of melatonin with non-pharmacological sleep interventions in tetraplegic populations?