Gastric Lavage in unselected acute organophosphate poisoning (OP)

Not Applicable

Completed

• Conditions: Organophosphate poisoning; Injury, Occupational Diseases, Poisoning

• Registration Number: ISRCTN24754520
• Lead Sponsor: Peking Union Medical College Hospital (China)

Brief Summary

2006 Protocol article in https://pubmed.ncbi.nlm.nih.gov/17049100/ (added 01/09/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2006-01-25
• Study Completion: 2009-03-01
• Last Update Posted: 13 September 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 908

Inclusion Criteria

All patients admitted to the medical wards with a history of acute organophosphate poisoning through stomach

Exclusion Criteria

1. Under the age of 18 years
2. Known to be pregnant
3. Have ingested other kinds of poison at the same time

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
All-cause mortality at hospital discharge.

Secondary Outcome Measures

Name	Time	Method
<br> 1. % of patients requiring intubation because of the respiratory failure<br> 2. Period of ventilation<br> 3. % of patients developing the intermediate syndrome (cranial nerve palsies and/or proximal weakness, without distal weakness, after resolution of the cholinergic crisis)<br> 4. Number of the organ dysfunction and 50% recovery time for blood acetylcholinesterase enzyme activity<br>