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Clinical Trials/NCT06331793
NCT06331793
Recruiting
Not Applicable

Use of a Wearable Device Which Generates an Electromagnetic Pulsed Field for Postoperative Analgesia of Mastectomies

European Institute of Oncology1 site in 1 country160 target enrollmentMay 9, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Female Breast Cancer
Sponsor
European Institute of Oncology
Enrollment
160
Locations
1
Primary Endpoint
Pain intensity
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

Study aim is to test AlgoCare, a device that uses the technology PEMF (Pulsed ElectroMagnetic Fields) for the treatment of postoperative pain in oncological breast surgery, in order to demonstrate that the use of Algocare in the postoperative period allows for a reduction in pain intensity in terms of Numerical Rating Scale (NRS) score and use of analgesic drugs.

Detailed Description

The treatment of postoperative pain is a priority issue for both the doctor and the patient. Obtaining adequate analgesia in the first postoperative days, in fact, is essential for the patient's comfort, but also to promote and accelerate functional recovery and prevent chronic pain, which in the case of breast surgery has a high incidence (20-60 %). The use of pulsed electromagnetic fields (PEMF) for the treatment of pain and inflammation has been widely studied and validated. Study aim is to test AlgoCare, a device that uses the technology PEMF (Pulsed ElectroMagnetic Fields), for the treatment of postoperative pain in oncological breast surgery. This is a field of application in which this technique analgesic has never been tested, but in which it could prove valid within a multimodal analgesia protocol, as the pain caused by this type of intervention is predominantly parietal and resulting from tissue trauma caused by the surgical wound. AlgoCare is a non-invasive and non-pharmacological device, developed specifically for treatment of post-operative inflammation and pain, CE certified and registered with the Ministry of Health. It emits a pulsed radio frequency electromagnetic field at 27.1 MHz, a frequency already studied and approved for medical use.

Registry
clinicaltrials.gov
Start Date
May 9, 2023
End Date
December 31, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
European Institute of Oncology
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Breast cancer patients undergoing unilateral mastectomy with reconstruction and without axillary dissection

Exclusion Criteria

  • Patients with PaceMakers (PMs), Implantable Cardioverter Defibrillators (ICDs), neurostimulators or other active medical devices or metal implants near the application area
  • Pregnancy
  • Amyloidosis, sarcoidosis, scleroderma, infectious arthritis, Paget's disease or joint tumors

Outcomes

Primary Outcomes

Pain intensity

Time Frame: 72 hours

Difference in mean NRS score between the two arms, at 24 hours and 72 hours after surgery (minimum value: 0, maximum value: 10 - higher scores mean a worse outcome)

Secondary Outcomes

  • Patient reported pain characteristics(3 months)
  • Need for other drugs(3 months)
  • Number of participants with other symptoms(3 months)
  • Need for analgesic drugs(3 months)
  • Wound healing timing(3 months)

Study Sites (1)

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