Physical Activity Levels and Functional Improvement in Breast Cancer Survivors
- Conditions
- Breast Cancer
- Interventions
- Other: Exercise Program
- Registration Number
- NCT04679090
- Lead Sponsor
- University of New Brunswick
- Brief Summary
The main objective of our project is to describe what characteristics (e.g., age, current physical activity level) women present when starting the exercise program are potentially associated with an improvement in functional abilities measured with different tests such as the distance you can cover while walking for six minutes.
- Detailed Description
The main research objective is to investigate the relationship between baseline physical activity and improvement in physical function, quantified using changes in 6-minute walk test (6MWT) results over the course of the 12-week program. An association is hypothesized to exist between the two variables even when adjusted for weeks into treatment. The goal of the 6MWT is to cover as much distance as possible in six minutes, using as many breaks s necessary. The test is often performed using a 20-meter hallway but requires no specific equipment. A recent study reported that the result of the 6MWT could be used as a measure of the major components of global health in women with breast cancer, making its use in our research especially relevant. Aside from physical functions, baseline characteristics will also be used to determine what characteristics, if any, are associated with health and psychosocial outcomes such as quality of life, social connectedness/support, and mental well-being. The data collected is certain to fill a gap in the literature, and will therefore be likely published in an important journal in the field.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 20
- Have received a diagnosis of breast cancer in your lifetime
- 19 years of age and older
- Cleared by medical team to participate in the study
- Have the intention to exercise at the facility for the duration of the study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Participant Exercise Program Participants will answer a series of questionnaires, wear a physical activity tracker (pedometer) and do functional tests (six minute walk test, chair stand test, balance, back scratch, sit and reach, leg strength and hand strength) pre and post.
- Primary Outcome Measures
Name Time Method Strength, Chair stand test Pre and post (after 12 weeks) Chair stand test, number of chair stand in 30 seconds
Walking speed Pre and post (after 12 weeks) 6-minute walk test (meters walked)
Strength, Hand grip Pre and post (after 12 weeks) Amount of force that can be exerted during grip squeeze (kg)
Balance Pre and post (after 12 weeks) One leg stand test (seconds)
Flexibility, back scratch test Pre and post (after 12 weeks) Back scratch test (cm)
Flexibility, sit and reach Pre and post (after 12 weeks) Sit and reach test
Physical Activity Level Pre and post (after 12 weeks) Pedometer to determine minutes in moderate-vigorous physical activity and steps per day
- Secondary Outcome Measures
Name Time Method Waist Circumference Pre and post (after 12 weeks) Measurement around the waist (cm)
Resting Blood Pressure Pre and post (after 12 weeks) Systolic and diastolic blood pressure (mmHg)
Pittsburgh Sleep Quality Index (PSQI) Pre and post (after 12 weeks) A self-report questionnaire that assesses sleep quality over a 1-month time interval
Godin-Shephard Leisure-Time Physical Activity Questionnaire Pre and post (after 12 weeks) Questionnaire used to identify self-reported leisure-time physical activity
Weight Pre and post (after 12 weeks) Weight of individual (kg)
Attendance Pre and post (after 12 weeks) Amount of exercise sessions attended during the 12-week program
Height Pre and post (after 12 weeks) Height of individual (cm)
Body-mass Index Pre and post (after 12 weeks) Measure of body fat based on height and weight (kg/m\^2)
Age Pre and post (after 12 weeks) Age (years)
FANTASTIC Lifestyle Checklist Pre and post (after 12 weeks) Meaningful improvement above day-to-day variability on the 6MWT
Resting Heart Rate Pre and post (after 12 weeks) Resting heart rate (beats per minute)
Functional Assessment of Cancer Therapy General (FACT - G) Pre and post (after 12 weeks) 27-item questionnaire designed to measure four domains of HRQOL in cancer patients: Physical, social, emotional, and functional well-being
Depression Anxiety Stress Scales (DASS) Pre and post (after 12 weeks) 42-item self report instrument designed to measure the three related negative emotional states of depression, anxiety and tension/stress.
Functional Assessment of Cancer Therapy Fatigue (FACT - F) Pre and post (after 12 weeks) 40-item measure that assesses self-reported fatigue and its impact upon daily activities and function
Trial Locations
- Locations (3)
University of Prince Edward Island
🇨🇦Charlottetown, Prince Edward Island, Canada
University of New Brunswick
🇨🇦Fredericton, New Brunswick, Canada
Memorial University of Newfoundland
🇨🇦St. John's, Newfoundland and Labrador, Canada