Pilot Study on the Feasibility of Using Smartphone Data as a Diagnostic Marker for Alzheimer's Disease
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 71
- 试验地点
- 1
- 主要终点
- Comparison of a mathematical combination
研究概览
简要总结
This study will compare smartphone usage data between three groups of patients diagnosed with either a memory complaint, mild cognitive decline, or Alzheimer's disease.
详细描述
Alzheimer's disease (AD) is the leading cause of dementia in the world. The first cognitive function affected is memory and then other cognitive systems are affected leading to a progressive loss of autonomy of the patient. Currently, the diagnosis of AD is made at too late a stage. Patients with memory complaints or mild cognitive decline (MCI) are particularly at risk of developing AD.
However, there is no clinical or paraclinical evidence to predict precisely this risk of progression to AD. Investigator's hypothesis is that there is an association between the evolution of smartphone use and the conversion of cognitive status to AD.
The purpose of this pilot study is to identify existing differences between smartphone use data of patients with a memory complaint or of patients MCI or with an AD. It is a study of 90 patients (30 patients with memory complaint, 30 with MCI and 30 with AD) with a collection of smartphone usage data during three months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient consulting in routine care in one of the CMRR
- •No sensory impairment that may compromise smartphone use
排除标准
- •Inability to perform MMSE or MMSE < 20 ;
- •Other neurodegenerative condition (Parkinson's disease, Lewy body disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis)
- •Severe anxiety or depressive disorder HADS score ≥ 17
- •Terminal phase of a severe disease
- •Evidence of a lesion on MRI that may be involved in cognitive impairment
研究组 & 干预措施
Alzheimer's Disease
干预措施: Recording of smartphone usage data (Other)
Memory complaint
干预措施: Recording of smartphone usage data (Other)
Mild cognitive decline
干预措施: Recording of smartphone usage data (Other)
结局指标
主要结局
Comparison of a mathematical combination
时间窗: Up to three months
The comparison of a mathematical combination of the different parameters collected during the three months of smartphone data recording
次要结局
未报告次要终点