The Effects of Hesperidin and Flaxseed in Prediabetes

Not Applicable

Completed

• Conditions: PreDiabetes
• Interventions: Other: control; Dietary Supplement: hesperidin and flaxseed

• Registration Number: NCT03737422
• Lead Sponsor: National Nutrition and Food Technology Institute

Brief Summary

To study the effects of Hesperidin and flaxseed supplement in patients with prediabetes, 50 patients will be randomly allocated to control group or 2 capsules Hesperidin and 30 gram flaxseed for 12 weeks; both groups will be advised to adherence the investigators' diet and exercise program too. At the first and the end of the intervention, lipid profiles, blood pressure, blood sugar, inflammatory and anthropometric factors will be assessed and compared between groups.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-01
• Primary Completion: 2018-10-01
• Study First Submitted: 2018-10-11
• Status Verified: 2018-11
• Study First Submitted QC: 2018-11-07
• Study First Posted: 2018-11-09
• Study Completion: 2018-12-01
• Last Update Submitted: 2019-07-24
• Last Update Posted: 2019-07-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• Age of 18 to 70 years prediabetes: impaired fasting glucose (>100 mg/dL) and/or HbA1C 5.7% to 6.5%, and overweight or obese with body mass index range of 25 to 40 kg/m2

Exclusion Criteria

• pregnancy or lactation
• A history of Cardiovascular disease, Pulmonary disease, Renal disease & Celiac disease; Cirrhosis
• Following program to lose weight in recent 3 mo

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
control	control	-
hesperidin and flaxseed	hesperidin and flaxseed	-

Primary Outcome Measures

Name	Time	Method
prediabetes	12 weeks	number of participants with normal plasma glucose

Trial Locations

Locations (1)

National Nutrition and Food Technology Research Institute; 🇮🇷 Tehran, Iran, Islamic Republic of