Spironolactone and Insulin Resistance in Chronic Heart Failure (CHF)
Phase 4
Completed
- Conditions
- Chronic Stable Heart Failure
- Registration Number
- NCT00664222
- Lead Sponsor
- Tottori University Hospital
- Brief Summary
The purpose of this study is to evaluate the effects of spironolactone and furosemide on insulin resistance in patients with chronic heart failure.
- Detailed Description
Diuretics is useful in CHF patients. On the other hand, they deteriorate glucose metabolism. Therefore, the purpose of this study is to evaluate the effects of spironolactone and furosemide on insulin resistance in patients with chronic heart failure.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
- chronic stable heart failure
Exclusion Criteria
- renal dysfunction or under treatment with antidiabetic agents
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method insulin resistance 16 weeks
- Secondary Outcome Measures
Name Time Method