NCT00664222已完成4 期
Effects of Spironolactone on Insulin Resistance in Patients With Chronic Heart Failure
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 16
- 主要终点
- insulin resistance
研究概览
简要总结
The purpose of this study is to evaluate the effects of spironolactone and furosemide on insulin resistance in patients with chronic heart failure.
详细描述
Diuretics is useful in CHF patients. On the other hand, they deteriorate glucose metabolism. Therefore, the purpose of this study is to evaluate the effects of spironolactone and furosemide on insulin resistance in patients with chronic heart failure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •chronic stable heart failure
排除标准
- •renal dysfunction or under treatment with antidiabetic agents
结局指标
主要结局
insulin resistance
时间窗: 16 weeks
次要结局
未报告次要终点
研究者
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