NL-OMON52903
Recruiting
Phase 2
[18F]PEG-Folate PET-CT imaging for monitoring of therapy response in Rheumatoid Arthritis patients - Monitoring of therapy response with PET-CT imaging in RA
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Vrije Universiteit Medisch Centrum
- Enrollment
- 20
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients must be at least 30 years of age
- •Diagnosis of rheumatoid arthritis according to the 1987 revised criteria of
- •the American Rheumatism Association (ARA)13 and/or the 2010 ACR/EULAR
- •Rheumatoid Arthritis classification criteria.
- •Patients with clinically active disease as assessed by a physician; with
- •arthritis in at least one synovial biopsy accessible joint and have a clinical
- •indication to start or restart (if stopped \>12 weeks) with anti\-TNF (either
- •Infliximab, Etanercept, Adalimumab or Certolizumab).
- •Prior treatment with one anti\-TNF agent (Adalimumab, Certolizumab,
- •Etanercept, Golimumab or Infliximab) is permitted, but may not be a primary
Exclusion Criteria
- •Use of intramuscular or intravenous corticosteroids within 4 weeks prior to
- •Patients who received methotrexate and folic acid less than 7 days before
- •tracer injection.
- •Treatment with any investigational drug within the previous 3 months
- •Known pregnancy or breast feeding
- •Research related radiation exposure (cumulative \>\=5 mSv) in the year before
Outcomes
Primary Outcomes
Not specified
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