Secondary data analysis on the implementation of guideline recommendations for the management of patients with hypercholesterolaemia and cardiovascular risk in routine general practice

• Conditions: E78; Disorders of lipoprotein metabolism and other lipidaemias

• Registration Number: DRKS00032936
• Lead Sponsor: MEDI-Ärzte vorOrt GmbH

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-10-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40000

Inclusion Criteria

All patient data collected within the practice data collection period and anonymised.

Exclusion Criteria

Lack of anonymisation

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluating guideline adherence in the management of patients with hypercholesterolaemia and cardiovascular risk in general practice by analysing possible changes in prescribing and treatment modalities regarding the prescription of statins (including dose and prescription of combination products) after the introduction of the new ESC treatment guideline in 2019.

Secondary Outcome Measures

Name	Time	Method
Measure treatment outcomes (reduction in LDL-C levels, overall cardiovascular risk, reduction in the number of clinically relevant events or diseases (e.g. arterial hypertension, atherosclerosis, coronary heart disease (CHD), heart failure, myocardial infarction (MI), stroke, chronic kidney disease, diabetes mellitus)) and side effects (e.g. nausea, vomiting, and especially muscle pain) before and after publication of the ESC treatment guideline in 2019.