Olfactory induced desensitization in patients with migraine - smell and migraine

niversitätsschmerzcentrum Universitätsklinikum Dresden0 个研究点目标入组 54 人开始时间: 2021年12月27日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1) Episodic Migraine with aura ie., = 1 migraine episode a month, but < 15 headache days a month
•2) Female sex
•3) Age between 18-55
•4) Normosmic, ie., no olfactory loss, TDI cutoff 30,75

•1) Current migraine attack
•2) fMRI incompatible: Claustrophobia; magnetic implants of any kind; tattoos with metallic ink on the neck, shoulders, upper arm, and head (could be heated in the scanner and possibly cause blistering or burning); pacemakers; Aneurysm clips and other vascular stents; filters or other devices; prosthetic heart valves and other prosthetic devices; neurostimulation devices; cochlear implants or ocular implants or known metal fragments in the eyes; exposure to shrapnel, metal fillings, or braces.
•3) Pregnant women
•4) Significant medical problems such as uncontrolled asthma or seizure disorder, acute heart disease, severe and unstable psychiatric problems and other neurological disorders (except migraine), other chronic pain that significantly affects the pat.'s ability to perform daily activities,
•Prefer patients without prophylactic migraine medication. Inclusion of acute medication: =10 days per month with acute analgesic medication, Exclusion of medication: no opioids, no cannabis, SNRI , valproate.
•5) Acute or chronic sinus problems.
•6) Inadequate communication skills

发起方

niversitätsschmerzcentrum Universitätsklinikum Dresden