NCT05852522招募中不适用
NCT MASTER Plattform Molecularly Aided Stratification for Tumor Eradication Research
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 10,000
- 试验地点
- 1
- 主要终点
- overall survival
研究概览
简要总结
NCT/DKFZ/DKTK MASTER is a prospective, continuously recruiting, multicenter observational study for biology-guided stratification of adults with rare cancers, including rare subtypes of common entities, using comprehensive molecular profiling, and clinical decision-making in a multidisciplinary molecular tumor board.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Rare cancer (Incidence <6/100,000 persons/year) or Rare subtype of a more common entity (case-by-case decision; example: pancreatic ductal adenocarcinoma without KRAS mutation)
- •Metastatic and/or locally advanced cancer with no curative therapy option and indication for systemic therapy
排除标准
- •Severe neurological or psychiatric disorder interfering with the ability to give oral and written informed consent
结局指标
主要结局
overall survival
时间窗: 10 years
time period of survival from date of diagnosis
progression free survival
时间窗: 5 years
Time period of progression survival from date of multiomics analysis
次要结局
- response to antitumor treatment(5 months)
研究者
研究点 (1)
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