ACTRN12612000710820尚未招募4 期
ovel Interventions in Heart Failure with Preserved Ejection Fraction -a single centre, randomised double blinded placebo cross-over pilot study using IVABRADINE, to assess the effect on 6 minute walk test, peak oxygen consumption and New York heart association Class of symptoms, from the Flinders Clinical Research group, Flinders University.
适应症
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Age greater than or equal to 18 years
- •HF-PEF (LVEF greater than or equal to 50% within 6m of randomisation)
- •NYHA II-III
- •Diastolic dysfunction on echo
- •E/A equal to 1, E/E’ equal to or greater than 15, deceleration time less than or equal to 140ms
- •Heart rate over 70/min
- •Stable disease, confirmed by no hospital admissions or HF medication changes within 3m prior to randomisation
- •Informed consent
- •No other causes for exertional dyspnoea
排除标准
- •Atrial Fibrillation
- •Contraindications to MRI
- •Significant valvular or coronary disease as primary cause of HF
- •Hypertrophic cardiomyopathy, cardiac amyloidosis, sarcoidosis
- •GFR equal to or greater than 45 ml/min
研究者
相似试验
尚未招募
4 期
ovel Interventions in Heart Failure with Preserved Ejection Fraction using TadalafilHeart Failure with Preserved Ejection FractionCardiovascular - Other cardiovascular diseasesACTRN12612000684820South Australian Health and Medical Reseasrch Institute20
尚未招募
不适用
The effect of a short term, supervised exercise training intervention on longitudinal left ventricular function in patient with heart failure with preserved ejection fractioHeart failure with preserved ejection fractionCardiovascular - Other cardiovascular diseasesACTRN12614001042639Sidhi Laksono Purwowiyoto25
已完成
不适用
Optimized heart failure therapy through continuous monitoring. The PHARAO multi-centre study10019280heart failureNL-OMON36743Kennemer Gasthuis30
已完成
不适用
The Current State of heart failure with preserved ejection fraction in Japan: From Etiology to Treatmentheart failureJPRN-UMIN000033436Shonan Fujisawa Tokushukai Hospital30,000
已完成
不适用
eural Cardiac Therapy for Heart Failure Studycardiac remodeling10019280Heart failureNL-OMON46859Boston Scientific20