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Hemodynamic Response During Goal Directed Fluid Therapy in the OR

Not Applicable
Terminated
Conditions
Hemodynamic Instability
Interventions
Procedure: Initial bolus pre-incision
Registration Number
NCT02365688
Lead Sponsor
Medtronic - MITG
Brief Summary

The purpose of this study is to retrospectively evaluate the hemodynamic response to goal directed fluid therapy fluid during open abdominal surgery where goal directed fluid therapy is a standard of care after establishing a pre-incision baseline response to fluids.

Detailed Description

Electronic and annotated observation data to support an algorithm library

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
18
Inclusion Criteria
  1. Adults ≥18 years booked for an open abdominal procedure
  2. American Society of Anaesthesiologists (ASA) Physical Status 1 - 3
  3. Expected duration of surgical procedure to be ≥ 2 hours
  4. Standard of care monitoring to include cardiac output
Exclusion Criteria
  1. Open chest surgical procedure expected
  2. Cardiac arrhythmia such as atrial fibrillation.
  3. Right Ventricular Failure
  4. Aortic regurgitation

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Initial bolus pre-incisionInitial bolus pre-incisionInitial pre-incision bolus of 500 cc of fluids with hemodynamic response recorded
Primary Outcome Measures
NameTimeMethod
Dynamic Hemodynamic Response to Fluid ResuscitationUp to 6 hours but not to exceed duration of surgical procedure

Physiological parameters compared before and after fluid bolus for fluid resuscitation.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Duke University Medical Center

🇺🇸

Durham, North Carolina, United States

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