Graft selection in anatomic anterior cruciate ligament reconstruction Patella, hamstrings or quadriceps tendon autograft

Recruiting

• Conditions: Anterior cruciate ligament rupture; 10005942; 10005944

• Registration Number: NL-OMON46939
• Lead Sponsor: Ziekenhuisgroep Twente

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 439

Inclusion Criteria

• Patients active in sports, Tegner =/>5
• Primary ACL rupture, evident from anamnesis (acute trauma, snapping sensation, swelling within several hours, feeling of instability), physical examination (positive Lachman test, anterior drawertest and/or pivot shift test), radiograph and MRI
• Willing to comply to the suggested (nationwide standard) rehabilitation protocol, supervised by a NFVS registerd sport-physical therapist
• <6 months between initial trauma and surgery

Exclusion Criteria

• History of knee surgery on the same side
• History of tendon removal on the same side
• Accompanying ligament injury of the knee, evident from anamnesis, physical examination, radiograph and MRI, defined as an ACL rupture in combination with a posterior cruciate ligament or collateral ligament injury,
• Peroperative discovery of cartilage damage; larger than 2cm2 and more than 50% depth
• Peroperative discovery of meniscus injury which requires a meniscectomy of more than 20% or meniscus sutures
• Osteoarthritis of Kellgren and Lawrence grade 2 or more, as evident from the radiograph
• Severe malalignment of the leg
• Tendency to form excessive scar tissue, such as arthrofibrosis
• Muscular, neurological or vascular anomalies that influence healingtime or rehabilitation
• Infection
• Known hypersensitivity to any of the used materials
• Long term relevant medication use such as prednisolone or cytostatics
• Pregnancy at the time of inclusion or surgery
• Known osteoporosis

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Failure= presence of pathological laxity, complaints of knee instability in the<br /><br>absence of any pathological laxity and/or discontinuïty of the graft on MRI or<br /><br>arthroscopy.</p><br>