NCT05397314已完成不适用
DNA Fragmentation - Effect on Pregnancy Rate
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 主要终点
- Sperm DNA fragmentation
研究概览
简要总结
The purpose of this study is to determine whether Punalpin, an antioxidant, has a positive impact on DNA fragmentation in spermatozoa in male fertility patients with increased amount of DNA fragmentation in their spermatozoa. Secondary purpose is to investigate whether there is any positive effect on the subsequent pregnancy rates from the fertility treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male fertility patients with increased amount of DNA fragmentation in their spermatozoa
排除标准
- 未提供
研究组 & 干预措施
Placebo
Placebo Comparator
干预措施: Placebo (Other)
Punalpin
Experimental
干预措施: Punalpin (Dietary Supplement)
结局指标
主要结局
Sperm DNA fragmentation
时间窗: 4 months
Reduction in DNA fragmentation
次要结局
未报告次要终点
研究者
Jens Fedder
Professor
Odense University Hospital
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