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临床试验/NL-OMON52945
NL-OMON52945已完成不适用

Determination of insulin-stimulated hepatic glucose uptake by PET-CT measurements - Insulin-stimulated hepatic glucose uptake

niversiteit Maastricht0 个研究点目标入组 15 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
15

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 64(—)

入选标准

  • - Caucasian (people will be excluded when having a *50% racial African/Asian
  • background)
  • - Male or postmenopausal female
  • - Aged 45-75 years
  • - Body mass index (BMI) 27 * 38 kg/m2
  • - Stable dietary habits (no weight loss or gain >3kg in the past 3 months)
  • - Sedentary lifestyle (not more than 2 hours of vigorous exercise per week)

排除标准

  • - Type 2 diabetes (fasted blood glucose > 7mmol/l)
  • - Any condition or medical history that would in the investigator*s or
  • dependent physician's opinion interfere with the study, with study outcomes or
  • increase the risk of the study procedures
  • - Alcohol consumption of >2 servings per day
  • - Use of medication known to interfere with the safety of study procedures
  • - Use of medication known to increase liver fat, like for instance
  • corticosteroids (parenteral & oral chronic administration only), amiodarone
  • (Cordarone), tamoxifen (Nolvadex), and methotrexate (Rheumatrex, Trexall).
  • - Subjects receiving thiazoledinediones (glitazones [pioglitazone,
  • rosiglitazone]).
  • - Participation in research or medical examination that included PET/CT
  • scanning in the last 3 months
  • -Contra-indication for MRI
  • -Low Hb(men: <8.6 mmol/L; women < 7.4 mmol/L)

研究者

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