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Clinical Trials/ISRCTN61965252
ISRCTN61965252
Completed
Phase 4

A randomized, double-blind, controlled trial to evaluate the efficacy and safety of a combination of xyloglucan and gelose associated to oral rehydration salts for the treatment of acute diarrhea in children (iDEA STUDY)

OVENTURE S.L.0 sites100 target enrollmentApril 24, 2020

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Acute diarrhea
Sponsor
OVENTURE S.L.
Enrollment
100
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

2021 results in https://pubmed.ncbi.nlm.nih.gov/33028102/ (added 12/05/2021)

Registry
who.int
Start Date
April 24, 2020
End Date
November 29, 2019
Last Updated
4 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
OVENTURE S.L.

Eligibility Criteria

Inclusion Criteria

  • 1\. Acute gastroenteritis defined as a change in stool consistency according to the Bristol Stool Form (BSF) scale and/or an increase in the frequency of evacuations (typically \=3 in 24 h) lasting more than 1 day and no longer than 3 days
  • 2\. Age group of children between \= 3 months and \= 14 years
  • 3\. A caregiver must provide written informed consent

Exclusion Criteria

  • 1\. Use of antibiotics, gelatine tannate, diosmectite, other probiotics, racecadotril, or zinc (including zinc containing ORS) within a week prior to enrolment
  • 2\. Exclusive breast feeding
  • 3\. Chronic diarrheal gastrointestinal disease (eg. inflammatory bowel diseases, cystic fibrosis, coeliac disease, food allergy)
  • 4\. Immunodeficiencies
  • 5\. Malnutrition (weight/height/length under 3rd percentile) (WHO Child Growth Standards will be used)
  • 6\. If needed, discontinuation or modification of the treatment may be considered at the discretion of the physician

Outcomes

Primary Outcomes

Not specified

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