Clinical Presentation and Outcome of COPD Patients With Acute Exacerbation Attending Sohag University Hospital
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 200
- 主要终点
- Clinical Presentation and Outcome of COPD Patients With Acute Exacerbation Attending Sohag University Hospital
研究概览
简要总结
Chronic obstructive pulmonary disease (COPD) is a worldwide public health challenge because of high prevalence and related disability and mortality (1).
Acute exacerbation of COPD (AECOPD), defned as the worsening of respiratory symptoms and requirement of additional clinical treatment, it reduces lung function and quality of life, and is accompanied by an increased disease-related burden, high hospital mortality and poor outcome (2).
Chronic obstructive pulmonary disease frequently coexists with other chronic diseases, namely comorbidities. They negatively impact prognosis, exacerbations and quality of life in COPD patients. Local and systemic inflammation have been proposed as having a potential role in explaining the association between COPD and these comorbidities (3).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with a confirmed COPD diagnosis according to (GOLD) guidelines, presented with acute exacerbation
排除标准
- •Stable COPD
- •Any other chronic chest diseases; Bronchial asthma or bronchiectasis
结局指标
主要结局
Clinical Presentation and Outcome of COPD Patients With Acute Exacerbation Attending Sohag University Hospital
时间窗: 1 year
Detection which patient with COPD exacerbation has more risk of survival or mortality
次要结局
未报告次要终点
研究者
Mona Abdelaleem Hussien
Resident doctor at chest department Sohag University Hospital
Sohag University