A Randomized Prospective study to see the Efficacy and Safety of KETAMINE added to BUPIVACAINE 0.25% in USG guided Modified Pectoral Block for management of postoperative pain in patients undergoing Modified Radical Mastectomy

With due approval from institutional ethical committee study will be conducted on 80 female breast carcinoma patients undergoing Modified Radical Mastectomy under General Anaesthesia. A written informed consent will be taken prior to procedure. Participants will be alotted into two groups, Group B will be receiving USG guided infiltration of inj Bupivacaine 0.25% 30ml as Pectoral  Block  and Group BK will be receiving  USG guided infiltration of inj Bupivacaine 0.25% 29ml with inj Ketamine 50mg(1ml) as Pectoral  block  prior to surgery. Participants will be followed in postoperative period for the duration of analgesia, total analegesia  consumption, haemodynamic side effects till patients first complain of pain or demands for analgesia . Data will be recorded and analysed using standard qualitative and quantitative tests , the p value of less than 0.05 will be considered significant.