NCT04660487招募中不适用
Relationship Between the Utilization and Degradation Rate of "FODMAPs" by Intestinal Flora and "GVHD"
The First Affiliated Hospital of Soochow University1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2020年12月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Occurrence of GVHD
研究概览
简要总结
With the stem cell transplanting increasing, patients which effected with "GVHD" were also increased. To evaluation the relationship between "FODMAPs" and "GVHD", Bone marrow transplant patients were recruited.
详细描述
The feces were collected from the patients who had been successfully transplanted after bone marrow transplantation. After 24 hours of culture in the culture medium, the degradation rate of "FODMAPs" was detected, and the relationship between the degradation rate and the occurrence time and degree of "GVHD" was observed
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of "AML","ALL","MDS" or "MM" Disease;
- •Must be treated with bone marrow transplantation;
- •The transplanted bone marrow was successfully planted
排除标准
- •Gastrointestinal diseases；
- •Age>60; or Age<10；
- •Probiotics or prebiotics were taken before enrollment
结局指标
主要结局
Occurrence of GVHD
时间窗: 90 days
The occurrence time and degree of GVHD
次要结局
未报告次要终点
研究者
Qi Xiao-Fei
Dean
The First Affiliated Hospital of Soochow University
研究点 (1)
Loading locations...
相似试验
招募中
不适用
FMT in Gut aGVHD TreatedAcute-graft-versus-host DiseaseNCT03148743The First Affiliated Hospital of Soochow University50
已完成
2 期
Alemtuzumab and Cyclosporine for the Prevention of Graft vs Host Disease After Stem Cell TransplantsGraft Versus Host DiseaseBone Marrow TransplantationNCT00775632University Health Network, Toronto78
已完成
不适用
Immune Monitoring After Allogeneic Hematopoietic Stem Cell TransplantationAllogeneic Stem Cell TransplantationGVHDNCT03233659IRCCS Azienda Ospedaliero-Universitaria di Bologna177
招募中
2 期
Evaluation of Recombinant Humanized Anti-CD25 Monoclonal Antibody for Preventing Graft-versus-host Disease After Haploidentical/matched Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients with Transfusion-dependent ThalassemiaTransfusion Dependent ThalassemiaNCT06657391Rongrong Liu396
已完成
不适用
Virtual Rehabilitation in HCTHematopoietic Cell TransplantNCT05943964Emory University20