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A clinical trial to evaluate duration of caffeine therapy for apnea of prematurity in preterm newborn.

Not Applicable
Conditions
Health Condition 1: P284- Other apnea of newborn
Registration Number
CTRI/2023/09/057347
Lead Sponsor
ikhil Kumar
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

All babies with birth gestation between 28 to 32 weeks on caffeine therapy.

Exclusion Criteria

antenatally detected congenital anomalies

parents not giving consent

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To estimate the proportion of infants between 28 to 32 weeks of gestational age who have clinically significant apnea on stopping caffeine after an apnea free period of 7 days. <br/ ><br>Clinically Significant Apnea defined as drop in saturation below 80% and any one of the following: <br/ ><br>(a) decrease in heart rate below 100/min. <br/ ><br>(b) Poor respiratory effort requiring PPV. <br/ ><br>(C)Need for o2 supplementation,HHFNC,CPAP,MV.(d)Restart of caffeine therpy by clinical team.Timepoint: From birth to 7 days of apnea free and off respiratory support.
Secondary Outcome Measures
NameTimeMethod
1. To study the adverse effects related to caffeine among neonates. <br/ ><br> <br/ ><br>2.To study the factors associated with clinically significant apnea after an apnea free period of 7 dayTimepoint: From birth till rooming in.
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