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Clinical Trials/NCT04706338
NCT04706338UnknownNot Applicable

A Study of Transcranial Magnetic Stimulation in the Rehabilitation of Glioma Patients With Postoperative Motor Dysfunction.

Beijing Neurosurgical Institute1 site in 1 country30 target enrollmentStarted: January 15, 2021Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Enrollment
30
Locations
1
Primary Endpoint
Accelerate motor functional recovery

Study Overview

Brief Summary

This study focused on glioma patients with postoperative motor deficits, especially for patients with supplementary motor area syndrome. The investigators want to investigate whether the recovery of motor function will be accelerated by using transcranial magnetic stimulation to stimulate primary motor area and supplementary motor area on the lesional hemisphere.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to 70 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •patient underwent awake craniotomy and motor functional identification during tumor resection;
  • •patients with postoperative motor deficit (muscle strength of limbs is weaker than preoperative status)

Exclusion Criteria

  • •patients with contraindication of transcranial magnetic stimulation;
  • •patients without data of the pre- and postoperative resting state MRI and diffusion tensor image.

Arms & Interventions

TMS treatment

Experimental

Patients with TMS treatment

Intervention: TMS treatment (Device)

Outcomes

Primary Outcomes

Accelerate motor functional recovery

Time Frame: From the day of tumor resection to 3 months after tumor resection.

The ratio of motor functional recovery in patients with TMS treatment is higher than those do not receive TMS treatment and the time of motor funcitonal recovery is shorter than those do not receive.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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