Transcranial Magnetic Stimulation in the Rehabilitation of Postoperative Motor Dysfunction.

Not Applicable

• Conditions: Postoperative Motor Deficit; Glioma
• Interventions: Device: TMS treatment

• Registration Number: NCT04706338
• Lead Sponsor: Beijing Neurosurgical Institute

Brief Summary

This study focused on glioma patients with postoperative motor deficits, especially for patients with supplementary motor area syndrome. The investigators want to investigate whether the recovery of motor function will be accelerated by using transcranial magnetic stimulation to stimulate primary motor area and supplementary motor area on the lesional hemisphere.

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-01
• Study First Submitted: 2021-01-10
• Study First Submitted QC: 2021-01-10
• Study First Posted: 2021-01-12
• Last Update Submitted: 2021-01-12
• Last Update Posted: 2021-01-14
• Study Start: 2021-01-15
• Primary Completion: 2021-06-01
• Study Completion: 2022-01-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. patient underwent awake craniotomy and motor functional identification during tumor resection;
2. patients with postoperative motor deficit (muscle strength of limbs is weaker than preoperative status)

Exclusion Criteria

1. patients with contraindication of transcranial magnetic stimulation;
2. patients without data of the pre- and postoperative resting state MRI and diffusion tensor image.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
TMS treatment	TMS treatment	Patients with TMS treatment

Primary Outcome Measures

Name	Time	Method
Accelerate motor functional recovery	From the day of tumor resection to 3 months after tumor resection.	The ratio of motor functional recovery in patients with TMS treatment is higher than those do not receive TMS treatment and the time of motor funcitonal recovery is shorter than those do not receive.

Trial Locations

Locations (1)

Beijing Neurosurgical Institute and Beijing Tiantan Hospital; 🇨🇳 Beijing, Beijing, China