Microbiological Evaluation of the Ocular Flora Before Cataract Surgery
- Conditions
- Disorders of the Eye Following Cataract Surgery
- Registration Number
- NCT02124603
- Lead Sponsor
- SIFI SpA
- Brief Summary
The purpose of the present study is to elucidate the spectrum of ocular flora and their antimicrobial susceptibility profiles in patients undergoing routine cataract surgery.
- Detailed Description
A conjunctival and palpebral swab will executed at least 14 days before routine cataract surgery. Isolates will be identified using standard microbiological protocols. In vitro susceptibility will be determined using a breakpoint minimal inhibitory concentrations. In case of positivity, the swab will be repeated the day of surgery. Topical antibiotic may be used in case of positivity at the discretion of the surgeon. Descriptive statistics will be calculated.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 120
- Patients scheduled for cataract surgery
- Age > 18 years
- Any gender and race
- Willing to sign informed consent
- Any antibiotics within 3 months
- Any ocular infection within 3 months
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Positive Culture in Subjects Scheduled for Cataract Surgery At least 14 days before surgery Number of participants with positive culture at the screening visit
- Secondary Outcome Measures
Name Time Method Antibiotic Susceptibility At least 14 days before surgery Isolated bacteria were tested for their in vitro susceptibility to commercially available ophthalmic antibiotics by the disk diffusion test and categorized as susceptible, intermediate or resistant.
Eradication Rate Day of surgery Number of participants having positive culture at the screening visit with bacterial eradication before surgery
Trial Locations
- Locations (1)
Casa di Cura Di Stefano
🇮🇹Catania, Italy