Evaluation of Ocular Flora in Patients Undergoing Cataract Surgery. An Observational Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Disorders of the Eye Following Cataract Surgery
- Sponsor
- SIFI SpA
- Enrollment
- 120
- Locations
- 1
- Primary Endpoint
- Positive Culture in Subjects Scheduled for Cataract Surgery
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The purpose of the present study is to elucidate the spectrum of ocular flora and their antimicrobial susceptibility profiles in patients undergoing routine cataract surgery.
Detailed Description
A conjunctival and palpebral swab will executed at least 14 days before routine cataract surgery. Isolates will be identified using standard microbiological protocols. In vitro susceptibility will be determined using a breakpoint minimal inhibitory concentrations. In case of positivity, the swab will be repeated the day of surgery. Topical antibiotic may be used in case of positivity at the discretion of the surgeon. Descriptive statistics will be calculated.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients scheduled for cataract surgery
- •Age \> 18 years
- •Any gender and race
- •Willing to sign informed consent
Exclusion Criteria
- •Any antibiotics within 3 months
- •Any ocular infection within 3 months
Outcomes
Primary Outcomes
Positive Culture in Subjects Scheduled for Cataract Surgery
Time Frame: At least 14 days before surgery
Number of participants with positive culture at the screening visit
Secondary Outcomes
- Antibiotic Susceptibility(At least 14 days before surgery)
- Eradication Rate(Day of surgery)