An observational study using perfusion index as predictor of hypotension following thiopentone induction in General anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To determine the baseline perfusion index(PI) and its variability in predicting hypotension following induction with intravenous propofol during general anaesthesia
研究概览
简要总结
This study will be undertaken after obtaining the Institutional Ethical Committee clearance.Subject will be recruited based on inclusion and exclusion criteria.Participants will be first explained what procedure is to be done in detail with its advantages and disadvantages during pre-anesthetic assessment. Informed consent will be obtained from all the patients following which demographic details including age and sex, along with detailed medical history and other comorbid conditions will be noted.All inpatients belonging to ASA I and ASA II undergoing elective surgery under general anaesthesia in SVMCH&RC who fulfill the inclusion criteria will be enrolled in the study afterIEC approval.On the day of surgery,all monitors will be attached, an electrocardiogram,non invasive blood pressure(NIBP) and pulse oximetry(B125M patient monitor)will be placed on the index finger contralateral to the side of the blood pressure cuff.Pre induction values of perfusion index(PI),Heart rate(HR),systolic blood pressure(SBP) diastolic blood pressure(DBP) and mean arterial blood pressure(MAP) will be noted.Routine general anaesthesia steps will be followed as per institutional protocol.Perfusion index(PI),Heart rate(HR),systolic blood pressure(SBP) diastolic blood pressure(DBP) and mean arterial blood pressure(MAP)will be recorded at a timeline 1 minute,2minute,3 minute,5 minute following thiopentone induction and 1 minute, 2minute,5 minute,10 minute and 15 minute post intubation.All study parameters will be assesed by the primary investigator.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1.patient of either sex with age limit of 18 to 60 years 2.ASA class1 and ASA class2 3.Patients who are electively posted for surgery under general anaesthesia using thiopentone as an inducing agent.
排除标准
- •1.Patients with uncontrolled diabetes mellitus and hypertension 2.Pregnant females 3.Patients with neurological or psychiatric illness, chronic pain disorder,peripheral vascular disease,ischemic heart disease 4.Patient with autonomic dysfunction or on drugs which affect autonomic dysfunction 5.Allergy to any drug used in the study 6.Hemodynamically unstable patients 7.Patients who refused to give consent.
结局指标
主要结局
To determine the baseline perfusion index(PI) and its variability in predicting hypotension following induction with intravenous propofol during general anaesthesia
时间窗: pre-induction;1 min 2 min 3 min 5 min post induction;1 min 2 min 5 min 10min 15 min post intubation
次要结局
- To look for association of perfusion index with haemodynamic parameters such as heart rate(HR),oxygen saturation(spo2),systolic blood pressure(SBP),diastolic blood pressure(DBP) and mean arterial blood pressure(DBP)(pre-induction;1min 2min 3min 5 min post induction;1min 2 min 5 min 10 min 15 min post intubation)
研究者
SASEETHA S K
Sri Venkateshwaraa medical college hospital and research center