Multimodal neuroimaging study of regulating menstruation and promoting pregnancy acupuncture therapy in patients with polycystic ovary syndrome

Phase 1

• Conditions: polycystic ovarian syndrome

• Registration Number: ITMCTR2200006569
• Lead Sponsor: Shandong Provinicial Third Hospital,Shandong University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

PCOS:

? Sparse ovulation or anovulation (clinical manifestations are sparse menstruation and amenorrhea);

? Clinical and/or biochemical features of hyperandrogenemia;

? Polycystic changes in ovary.

Two of the above three are true.

Healthy women:

Good physical condition, regular menstrual cycle, normal ovarian function, normal gynecological color doppler ultrasound, right-handedness, no organic or serious functional diseases, no history of mental illness, no MRI contraindications, etc.

? Women aged 18-40;

? Right hand;

? No acupuncture treatment in the past 1 month;

? Those who voluntarily participated in the experiment and insisted on treatment and signed informed consent.

Exclusion Criteria

? Complicated with other endocrine system diseases, including congenital adrenal hyperplasia, adrenal tumor, Cushing's syndrome, ovarian or adrenal tumor secreting androgen, pituitary prolactinoma, diabetes mellitus, thyroid disease, etc.

? Complicated with serious primary diseases, such as serious diseases of cardiovascular and cerebrovascular system, respiratory system, liver, kidney, digestive system, blood system, immune system and neuropsychiatric system;

(3) history of thrombosis or thromboembolism;

(4) Substance abuse in the past 3 months, including serious alcohol abuse, smoking (1 pack or more per day), drug abuse;

? Taking dingkundan or Dayin-35 or other oral contraceptives and sex hormone drugs within the last 3 months;

? Pregnant and lactating women, and women within 1 year after delivery;

There are metal in the body, claustrophobia and other mri contraindications.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
euroimaging index;LH/FSH;

Secondary Outcome Measures

Name	Time	Method
Ferriman-gallway Hair Rating Scale;Menstruation situation;Self-rating Depression Scale;GAGS table;self-rating anxiety scale;