Malnutrition and Outcome in Hospitalized Children in Europe (ESPEN Network Grant Project)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,567
- 试验地点
- 14
- 主要终点
- Length of Hospital Stay
研究概览
简要总结
Malnutrition in children has even more severe consequences on disease course and long-term health than malnutrition in adults. According to prior studies, malnutrition affects about 15-30 % of hospitalized children in Europe (ESPGHAN 2005, Pawellek et al 2008, Joosten and Hulst 2008). However, available criteria for defining malnutrition in paediatric patients are inconsistent, not based on firm evidence, and not generally agreed upon. Current guidelines do not address assessment of and screening for childhood malnutrition. Therefore, a large number of affected children are not adequately diagnosed.
One aim of this study is to assess the prevalence of malnutrition and patients at risk for malnutrition among at least 2700 hospitalized children mainly across Europe. In addition criteria to link anthropometric measurements and the prediction of outcome, i.e. length of hospital stay, shall be established. A further goal then is to establish agreed, evidence-based criteria for malnutrition in children with the purpose of leading to an agreed, evidence-based screening tool for paediatric malnutrition in developed countries. This tool shall include a set of simple questions, based on previously suggested tools. Thereby this study will provide a strong basis for implementing evidence-based nutritional interventions in paediatric patients by harmonisation of diagnostic criteria for childhood malnutrition in developed countries.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Month 至 18 Years(Child, Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children admitted to the participating hospitals during the study period
- •Age between 1 month and 18 years
- •Expected hospital stay exceeding 24 hours
- •Parents/caregivers, as well as those patients capable to comprehend, agree to participation and sign the informed consent form
排除标准
- •Infants with premature birth (<37 weeks gestational age) during the first 12 months of life
- •Infants < 1 month of age
- •Patients ≥ 18 years of age
- •Children in need of intensive care
- •Children admitted to day-care (LOS < 24hours)
- •Patients admitted for elective reasons with an expected hospital stay <24 hours
结局指标
主要结局
Length of Hospital Stay
时间窗: 60 days
Length of Hospital Stay will be compared between malnourished and non malnourished children.
次要结局
- muscle strength(within 24 hours after admission)
- infection as a complication during hospital stay(60 days)
- gastrointestinal complications (vomiting, diarrhoea)(60 days)
研究者
Koletzko - Office
Prof
Ludwig-Maximilians - University of Munich
