Can nutritional supplementation enhance molecular pathways responsible for building muscle following anterior cruciate ligament(ACL) injury?

Australian Catholic University0 个研究点目标入组 20 人开始时间: 2024年5月7日最近更新: 2024年5月13日

试验速览

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•Male or female
•Aged between 18 to 40 years
•One leg sustained an ACL injury within the last 5-years, but the participant can safely complete lower limb strength training.

•ACL injury without surgical reconstruction
•Any lower limb injury in the past 24-months that influences the quadriceps responses to exercise (e.g. muscle strain)
•Known cardiovascular disease or diabetes
•Known bleeding disorder (i.e. hemophilia A [factor VIII deficiency], hemophilia B [factor IX deficiency], von Willebrand disease, or other rare factor deficiencies including I, II, V, VII, X, XI, XII and XIII)
•Major or chronic illness that impairs mobility or eating/digestion
•Taking prescription medications (i.e. beta-blockers, anti-arrhythmic drugs, statins, insulin sensitising drugs, or drugs that increase the risk of bleeding [i.e. anticoagulants, antiplatelets, novel oral anticoagulants [NOAs], nonsteroidal anti-inflammatory drugs [NSAIDs], selective norepinephrine reuptake inhibitors [SNRI], or selective serotonin reuptake inhibitors [SSRIs])
•Any contraindications to MRI assessed via the Swinburne Neuroimaging MRI Safety Questionnaire and Consent Form.
•Individuals with allergy/intolerance to milk and/or milk products and/or seafood.

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