Evaluation of Lifetime participation in Intensive Top-level sports and Exercise
Recruiting
- Conditions
- - SCA/SCD- CMP - Arrhytmias - Congenital-, familiar-, and genetical- cardiovascular diseases.
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 3200
Inclusion Criteria
Aged 16 years and older
-Elite athlete (national-, or international level, and/or status athlete according to NOC*NSF)
-Participation in the SMART screening
COMMIT (sub-study)
-Tested positive for SARS-CoV-2 with RT-PCR (or according to other standard diagnostic protocols)
Exclusion Criteria
-Unable to give informed consent
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To establish a cardiac baseline of all elite athletes(national-, international level, or NOC*NSF status athletes).<br>2.To investigate changes in cardiac indices over time in all elite athletes engaging in intense physical activity.
- Secondary Outcome Measures
Name Time Method 3.To establish an elite athlete biobank to investigate genetic profiles and their association with cardiac indices<br>4.To quantify and investigate the prevalence and clinical consequences of myocardial involvement after COVID-19 in elite athletes (COMMIT).<br>Tertiary outcome:<br>5.To compare levels of antibody and T-cell responses to SARS-CoV-2 of athletes with those of mild and severe symptomatic patients with laboratory-confirmed SARS-CoV-2 infection (collaboration with RECoVERED study)<br>