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Clinical Trials/NCT05373823
NCT05373823
Recruiting
Not Applicable

A Digital Intervention to Improve Skin Self-examination Among Melanoma Survivors

Rutgers, The State University of New Jersey1 site in 1 country385 target enrollmentMarch 6, 2023

Overview

Phase
Not Applicable
Intervention
MySmartSkin enhancement
Conditions
Melanoma
Sponsor
Rutgers, The State University of New Jersey
Enrollment
385
Locations
1
Primary Endpoint
Body parts examined
Status
Recruiting
Last Updated
2 months ago

Overview

Brief Summary

This project, mySmartSkin (MSS), includes an innovative Type 1 hybrid effectiveness-implementation trial designed to enhance the effects of MSS and simultaneously assess key implementation outcomes (e.g., cost, adoption) as well as contextual factors important for scale-up in community and health care settings where melanoma survivors receive follow-up care. A type 1 hybrid effectiveness-implementation design allows us to engage multilevel stakeholders throughout this process, evaluate the effectiveness of the enhanced MSS, and identify critical factors for wide-scale implementation. Aim 1 will focus on enhancing the previous version of MSS by collaborating with multi-level stakeholders in qualitative interviews and usability testing. Aim 2 will evaluate the effects of enhanced MSS on thorough skin-self examinations (SSE) in a randomized-control trial (RCT) and examine its impact on the diagnosis of new/recurrent melanomas. Aim 3 will focus on assessing selected implementation outcomes and identify factors relevant to future scale-up for widespread dissemination and implementation.

Detailed Description

This is a type one hybrid effectiveness-implementation study consisting of three aims. Aim one (Months 1-15) focuses on MSS enhancement using stakeholder collaboration. Aim two (Months 16-60) involves the longitudinal randomized control trial (RCT) comparing behavioral outcomes and effectiveness of enhanced MSS versus an educational webpage. Aim three (Months 16-60) will assess implementation outcomes and identify contextual factors to facilitate scale-up for future dissemination and implementation.

Registry
clinicaltrials.gov
Start Date
March 6, 2023
End Date
March 31, 2027
Last Updated
2 months ago
Study Type
Interventional
Study Design
Sequential
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sharon Manne, PhD

Associate Director for Cancer Prevention, Control and Population Science

Rutgers, The State University of New Jersey

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of primary pathologic stage 0-III cutaneous malignant melanoma
  • Three months to five years post-surgery
  • No current evidence of cancer
  • Not adherent to thorough SSE (i.e., did not check entire body at least once during the past three months)
  • ≥ 18 years old
  • Internet access
  • Able to speak/read English
  • Able to provide informed consent

Exclusion Criteria

  • Not provided

Arms & Interventions

Enhance MSS using multi-level stakeholder collaboration (Mo.1-15)

Enhancements of MSS to increase intervention effects - theory - based strategies (PHM), (BCT)

Intervention: MySmartSkin enhancement

Involves the longitudinal RCT comparing behavioral outcomes and effectiveness (Mo.16 -60)

RCT of enhanced MSS testing effectiveness (thorough SSE, sun protection behavior Involves the longitudinal RCT comparing behavioral outcomes and effectiveness of enhanced MSS versus an educational webpage on SSE as well as new recurrences/melanomas

Intervention: Educational webpage on Skin Self-Examination

Aim 3: Assess implementation outcomes, identify factors relevant for future scale-up (Mo.17-60)

Assessment of implementation outcomes and key contextual factors from the perspective of multi - level stakeholders

Intervention: Assess implementation outcomes

Outcomes

Primary Outcomes

Body parts examined

Time Frame: 18 months

Yes/No for a list of body parts examined during most recent SSE in the last three months. This is the primary outcome because SSE thoroughness is associated with detection of thinner tumors. This will be assessed by Reach, Effectiveness, Adoption, Implementation, and Maintenance(RE-AIM) and Practical, Robust Implementation and Sustainability Model (PRISM).

Body parts examined

Time Frame: Baseline

Yes/No for a list of body parts examined during most recent SSE in the last three months. This is the primary outcome because SSE thoroughness is associated with detection of thinner tumors. This will be assessed by Reach, Effectiveness, Adoption, Implementation, and Maintenance(RE-AIM) and Practical, Robust Implementation and Sustainability Model (PRISM).

Body parts examined

Time Frame: 3 months

Yes/No for a list of body parts examined during most recent SSE in the last three months. This is the primary outcome because SSE thoroughness is associated with detection of thinner tumors. This will be assessed by Reach, Effectiveness, Adoption, Implementation, and Maintenance(RE-AIM) and Practical, Robust Implementation and Sustainability Model (PRISM).

Body parts examined

Time Frame: 6 months

Yes/No for a list of body parts examined during most recent SSE in the last three months. This is the primary outcome because SSE thoroughness is associated with detection of thinner tumors. This will be assessed by Reach, Effectiveness, Adoption, Implementation, and Maintenance(RE-AIM) and Practical, Robust Implementation and Sustainability Model (PRISM).

Body parts examined

Time Frame: 12 months

Yes/No for a list of body parts examined during most recent SSE in the last three months. This is the primary outcome because SSE thoroughness is associated with detection of thinner tumors. This will be assessed by Reach, Effectiveness, Adoption, Implementation, and Maintenance(RE-AIM) and Practical, Robust Implementation and Sustainability Model (PRISM).

Secondary Outcomes

  • Melanoma Diagnosis(3 months)
  • Melanoma Diagnosis Date(18 months)
  • Melanoma Stage(18 months)
  • Melanoma Diagnosis(6 months)
  • Melanoma Diagnosis(12 months)
  • Melanoma Diagnosis(18 months)
  • Melanoma Stage(3 months)
  • Melanoma Stage(6 months)
  • Melanoma Stage(12 months)
  • Melanoma Diagnosis Date(3 months)
  • Melanoma Diagnosis Date(6 months)
  • Melanoma Diagnosis Date(12 months)

Study Sites (1)

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