Compare the effect of clonidine and tizanidine in controlling pain after lumbar fusion surgery

Phase 3

• Conditions: Pain control after cesarean section.; Other acute postprocedural pain; G89.18

• Registration Number: IRCT20210904052371N1
• Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 November 2021

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Confirm the diagnosis by physical examination, CT scan and MRI
The patient's desire to participate in the study and gain informed consent
Candidate for non-emergency lumbar fusion surgery
Age between 70-35 years and
No history of tizanidine allergy
Absence of bradycardia (HR <60) in patients
Absence of CNS disease
No history of any previous back surgery

Exclusion Criteria

The patient's unwillingness to continue participating in the study at any time
Taking narcotic painkillers 24 hours before the intervention
Alcohol or drug abuse
Occurrence of any unusual complication during surgery

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intensity of patients' pain. Timepoint: 48 hours. Method of measurement: Visual Analogue Scale.;The amount of drugs used. Timepoint: 48 hours. Method of measurement: Visual Analogue Scale.

Secondary Outcome Measures

Name	Time	Method
The rate of nausea. Timepoint: 48 hours. Method of measurement: Visual Analogue Scale.;The rate of vomiting. Timepoint: 48 hours. Method of measurement: Visual Analogue Scale.;Itching rate. Timepoint: 48 hours. Method of measurement: Visual Analogue Scale.;Dry mouth. Timepoint: 48 hours. Method of measurement: Visual Analogue Scale.;Bradycardia rate. Timepoint: 48 hours. Method of measurement: Visual Analogue Scale.;Headache rate. Timepoint: 48 hours. Method of measurement: Visual Analogue Scale.;Vertigo. Timepoint: 48 hours. Method of measurement: Visual Analogue Scale.;The rate of drowsiness. Timepoint: 48 hours. Method of measurement: Visual Analogue Scale.