Cerebral Bases of Arithmetics Processing

Not Applicable

Completed

• Conditions: Neural Bases of Arithmetic Processing
• Interventions: Other: neuropsychological testing; Other: functional magnetic resonance imaging; Other: simple arithmetic operations

• Registration Number: NCT02899676
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

The aim of this study was to identify neural correlates involved in arthmetics processing in adults and children aged 8 to 14 with normal cognitive function. Brain area will be identified by functional magnetic resonance imaging (IRMf).

Detailed Description

Not available

Study Timeline

• Study Start: 2014-03-18
• Study First Submitted: 2016-09-02
• Study First Submitted QC: 2016-09-08
• Study First Posted: 2016-09-14
• Primary Completion: 2018-05-09
• Study Completion: 2018-05-09
• Status Verified: 2019-03
• Last Update Submitted: 2019-08-26
• Last Update Posted: 2019-08-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 79

Inclusion Criteria

• children aged 8 to 14 with parents' consent
• adults aged 18 to 24
• right-handed
• affiliated to the French social security

Read More

Exclusion Criteria

• known neurological disorders including epilepsia
• known psychiatric disorders including Attention Deficit Disorder
• birth complications needing intensive care
• central nervous system treatment
• important hearing disabilities
• not corrected impaired vision

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Healthy subjects aged 8 to 11	functional magnetic resonance imaging	Subjects without neurological or psychiatric history
Healthy subjects aged 12 to 14	neuropsychological testing	Subjects without neurological or psychiatric history
Healthy subjects aged 18 to 24	functional magnetic resonance imaging	Subjects without neurological or psychiatric history
Healthy subjects aged 18 to 24	simple arithmetic operations	Subjects without neurological or psychiatric history
Healthy subjects aged 8 to 11	neuropsychological testing	Subjects without neurological or psychiatric history
Healthy subjects aged 8 to 11	simple arithmetic operations	Subjects without neurological or psychiatric history
Healthy subjects aged 12 to 14	functional magnetic resonance imaging	Subjects without neurological or psychiatric history
Healthy subjects aged 12 to 14	simple arithmetic operations	Subjects without neurological or psychiatric history
Healthy subjects aged 18 to 24	neuropsychological testing	Subjects without neurological or psychiatric history

Primary Outcome Measures

Name	Time	Method
Brain area activity in arithmetic processing will be identified by IRMf	up to 60 days after inclusion	Brain activity is identified by IRMf

Secondary Outcome Measures

Name	Time	Method
Parietal region activity in arithmetic processing will be identified by IRMf	up to 60 days after inclusion	comparison between group aged to 12to 14 and group aged to 8 to 11

Trial Locations

Locations (1)

Médecine nucléaire, Groupement Hospitalier Est, HCL; 🇫🇷 Bron, France