Comparison of topical recombinant human epidermal growth factor versus aloe vera gel in combination with ablative 10,600-nm carbon dioxide fractional laser for the treatment of striae alba: A randomized, double-blind trial
Not Applicable
Completed
- Conditions
- Striae albastriae alba,recombinant-human epidermal growth factor,fractional carbon dioxide laser
- Registration Number
- TCTR20180610001
- Lead Sponsor
- Thammasat University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
subjects aged 20-60, in good health, with striae alba on both sides of abdomen, thigh or buttock, able to remain 5kg of their starting weight during the study and avoid any non-study treatment of striae during the whole study period
Exclusion Criteria
history of keloids or hypertrophic scar, skin infection or other active skin disease on the study areas, use of immunosuppressive drug or systemic retinoid within past 2 months, any treatment including laser for striae within 1 year prior to study initiation, allergy to local anesthesia (e.g. lidocaine or prilocaine).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Texture of striae, Average malanin and melanin variation 9 months Anthera 3D Image
- Secondary Outcome Measures
Name Time Method Side effectes such as erythema, scab and postinflammatory hyperpigmentation 9 months Investigator assessment