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A comparative clinical study to evaluate the safety and performance of capsular tension ring.

Phase 4
Conditions
Health Condition 1: H259- Unspecified age-related cataract
Registration Number
CTRI/2023/03/050397
Lead Sponsor
Grewal Eye Institute
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Patients older than 12 years

2. Normal fundus examination

3. Patients for whom phacoemulsification is required of cataract

surgery

4. Patients with axial length >28 mm, or more than 3 months had

passed since Pars plana vitrectomy (PPV)

5. Patients with weak zonules along with any of this following

conditions

Inadequate zonular support

Patients with the pseudo-exfoliation syndrome

Trauma causing zonular dialysis

Phacodonesis

6. Patients who are eligible for phacoemulsification alone or

with CTR implants

7. Patients who are eligible for phacoemulsification alone or

with CTR implants

8. Patient willing to participate and sign informed consent forms.

9. Female participants of child bearing potential and male

participants whose partner is of child bearing potential

must be willing to ensure that they or their partner use

effective contraception during the study

Exclusion Criteria

1.Presence of a torn or compromised capsular

bag or significant, progressive

pseudoexfoliation

2.Patients with retinitis pigmentosa,

trauma, other intraocular surgeries than

PPV, or connective tissue disorders

3.Patients with chronic uveitis

4.Patients with progressive eye disease

(e.g. diabetic retinopathy, uncontrolled

glaucoma)

5.Patients with preoperative complications

prior to cataract surgery (e.g. vitreous

body prolapse, haemorrhage)

6.Patients with perforated or damaged

capsules

7.Patients with zonular damage larger than 4

clock hours

8.Zonular rupture >90º

9.Pregnancy (as stated by patient) and

lactation

10.Patients with concurrent participation in

another drug or medical device clinical

study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1)Refraction - Refractive prediction error - Measured as subjective refraction. Both spherical and astigmatism shall be measured by using phoropter.Timepoint: Time Frame: Pre-operative, 90 Days Post- operative surgery
Secondary Outcome Measures
NameTimeMethod
1)Visual Acuity-UDVA - The visual acuity upto 90 ± 7 days post- operative surgery, measured in LogMAR. LogMAR is the logarithm of the minimum angle of resolution. A lower logMAR value indicates better visual acuity. Visual acuity measured by ETDRS chart. <br/ ><br>2)Visual Acuity- BCDVA - The visual acuity upto 90 ± 7 days post- operative surgery, measured in LogMAR. LogMAR is the logarithm of the minimum angle of resolution. A lower logMAR value indicates better visual acuity. Visual acuity measured by ETDRS chart. <br/ ><br>3)IOL Tilt <br/ ><br>•IOL Tilt - Measured by Pentacam <br/ ><br>4)IOL Decentration - <br/ ><br>•IOL Decentration - Measured by Pentacam <br/ ><br>Timepoint: 1)Visual Acuity-UDVA -Time Frame: Pre-operative, 90 Days Post- operative surgery <br/ ><br>2)Visual Acuity- BCDVA -Time Frame: Pre-operative, 90 Days Post- operative surgery <br/ ><br>3)IOL Tilt and 4)IOL Decentration - Time Frame: 15 Days Post- operative surgery, 90 Days Post- operative surgery <br/ ><br>
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