PACTR202309486066044已完成4 期
Plethysmography variation index versus Pulse pressure variation as an indicator of fluid responsiveness in colorectal surgeries during immediate postoperative period.
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 103
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 19 Year(s) 至 44 Year(s)(—)
- 性别
- All
入选标准
- •1-Age =18 years and <65 years.
- •2-Patients admitted to the ICU after performing colorectal surgeries.
- •3- APACHE II SCORE will be done to all patients admitted to ICU after colorectal surgery.
- •4-Patients on controlled mechanical ventilation with tidal volume at least 8ml/kg and sedated.
- •5-Patients requiring intravenous fluid challenge for resuscitation based on the clinical characteristics as systolic arterial blood pressure (SBP) <90 mmHg or mean arterial pressure (MAP) <65 mmHg with signs of hypoperfusion (oliguria less than 0.5 ml/kg/h, arterial lactate >2.5 mMol/L).
- •6-Patients with an arterial catheter and central venous catheter via the internal jugular vein or the subclavian vein.
- •7-Patients with normal sinus rhythm.
排除标准
- •1-Un satisfactory cardiacechogenicity.
- •2-Preexisting severe valvular heart disease.
- •3-Known tricuspid insufficiency, intracardiac shunt or cardiac arrhythmia.
- •4-Low left ventricular function (ejection fraction < 40%).
- •5-Any contraindication to fluid resuscitation, such as congestive heart failure, evidence of fluid overload or renal dysfunction.
- •6-Lung pathologies (like asthma, COPD).
- •7-Patients with contraindications for sedation by narcotics and midazolam like hepatic or renal dysfunction.
- •8-Patients suffering from type I /II diabetes.
- •9-Patients whose temporary removal of the compression stocking owing to venous insufficiency (i.e., deep venous thrombosis) could endanger patient safety.
研究者
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