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临床试验/PACTR202309486066044
PACTR202309486066044已完成4 期

Plethysmography variation index versus Pulse pressure variation as an indicator of fluid responsiveness in colorectal surgeries during immediate postoperative period.

Faculty of medicine Ain shams university0 个研究点目标入组 103 人开始时间: 2023年8月28日最近更新:

试验速览

阶段
4 期
状态
已完成
入组人数
103

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
19 Year(s) 至 44 Year(s)(—)
性别
All

入选标准

  • 1-Age =18 years and <65 years.
  • 2-Patients admitted to the ICU after performing colorectal surgeries.
  • 3- APACHE II SCORE will be done to all patients admitted to ICU after colorectal surgery.
  • 4-Patients on controlled mechanical ventilation with tidal volume at least 8ml/kg and sedated.
  • 5-Patients requiring intravenous fluid challenge for resuscitation based on the clinical characteristics as systolic arterial blood pressure (SBP) <90 mmHg or mean arterial pressure (MAP) <65 mmHg with signs of hypoperfusion (oliguria less than 0.5 ml/kg/h, arterial lactate >2.5 mMol/L).
  • 6-Patients with an arterial catheter and central venous catheter via the internal jugular vein or the subclavian vein.
  • 7-Patients with normal sinus rhythm.

排除标准

  • 1-Un satisfactory cardiacechogenicity.
  • 2-Preexisting severe valvular heart disease.
  • 3-Known tricuspid insufficiency, intracardiac shunt or cardiac arrhythmia.
  • 4-Low left ventricular function (ejection fraction < 40%).
  • 5-Any contraindication to fluid resuscitation, such as congestive heart failure, evidence of fluid overload or renal dysfunction.
  • 6-Lung pathologies (like asthma, COPD).
  • 7-Patients with contraindications for sedation by narcotics and midazolam like hepatic or renal dysfunction.
  • 8-Patients suffering from type I /II diabetes.
  • 9-Patients whose temporary removal of the compression stocking owing to venous insufficiency (i.e., deep venous thrombosis) could endanger patient safety.

研究者

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