Plethysmography variation index versus Pulse pressure variation as an indicator of fluid responsiveness in colorectal surgeries during immediate postoperative period.

Phase 4

Completed

• Conditions: Circulatory System; fluid responsiveness in patients in icu after colorectal surgeries using dynamic indices as PVI; Anaesthesia

• Registration Number: PACTR202309486066044
• Lead Sponsor: Faculty of medicine Ain shams university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-28
• Last Update Posted: 2024-03-04

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 103

Inclusion Criteria

1-Age =18 years and <65 years.
2-Patients admitted to the ICU after performing colorectal surgeries.
3- APACHE II SCORE will be done to all patients admitted to ICU after colorectal surgery.
4-Patients on controlled mechanical ventilation with tidal volume at least 8ml/kg and sedated.
5-Patients requiring intravenous fluid challenge for resuscitation based on the clinical characteristics as systolic arterial blood pressure (SBP) <90 mmHg or mean arterial pressure (MAP) <65 mmHg with signs of hypoperfusion (oliguria less than 0.5 ml/kg/h, arterial lactate >2.5 mMol/L).
6-Patients with an arterial catheter and central venous catheter via the internal jugular vein or the subclavian vein.
7-Patients with normal sinus rhythm.

Exclusion Criteria

1-Un satisfactory cardiacechogenicity.
2-Preexisting severe valvular heart disease.
3-Known tricuspid insufficiency, intracardiac shunt or cardiac arrhythmia.
4-Low left ventricular function (ejection fraction < 40%).
5-Any contraindication to fluid resuscitation, such as congestive heart failure, evidence of fluid overload or renal dysfunction.
6-Lung pathologies (like asthma, COPD).
7-Patients with contraindications for sedation by narcotics and midazolam like hepatic or renal dysfunction.
8-Patients suffering from type I /II diabetes.
9-Patients whose temporary removal of the compression stocking owing to venous insufficiency (i.e., deep venous thrombosis) could endanger patient safety.

Study & Design

• Study Type: Interventional
• Study Design: Not specified