Gastrointestinal Microcirculation During Cardiopulmonary Bypass
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Blood Flow in Microcirculation
Study Overview
Brief Summary
O2C is a diagnostic device for non-invasive determination of oxygen supply in microcirculation of blood perfused tissues. The optical sensor is easy to handle and guarantees reproducible examinations of local oxygen supply of tissues in clinics as well as in research. The examinations are without any strain for your patient.
Determines by use of a glass fibre probe:
Blood Flow in Microcirculation Capillary-Venous Oxygen Saturation Blood Filling of Microvessels Blood Flow Velocity This device makes it possible to supervise the local oxygen supply of organs and tissue.
With it is possible to measure locally the amount of oxygen which is transported into the region of interest and to diagnose local oxygen consumption of an organ. O2C's novelty is monitoring the energetic metabolism of cells by measuring the oxygen uptake with an optical sensor probe. Pathological O2-supply, which can lead to angiogenesis or cell-death and subsequently to organ failure, now can be detected in an early state by use of the new sensor system.
One of these new developed sensors are used to place in rectal position during extracorporeal circulation to determine the microcirculation.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients on extracorporeal circulation
Exclusion Criteria
- •Haemorrhoidal lesions
Outcomes
Primary Outcomes
Blood Flow in Microcirculation
Time Frame: 3 hours
Secondary Outcomes
No secondary outcomes reported
Investigators
Arndt-H. Kiessling
Head cardiovascular research
Johann Wolfgang Goethe University Hospital
