NCT01891825暂停不适用
Persistent Atrial Fibrillation Ablation Trial
Neil Sulke4 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2014年9月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 发起方
- 入组人数
- 50
- 试验地点
- 4
- 主要终点
- Recurrence of persistent AF by 12 months after ablation
研究概览
简要总结
Persistent atrial fibrillation (AF) is a common and distressing condition, that can cause significant symptoms. AF ablation is a recognised technique to treat persistent AF, but can be technically difficult. This study compares percutaneous ablation to thoracoscopic surgical AF ablation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Symptomatic persistent or long-standing AF suitable for AF ablation.
- •Age over 18 years old.
- •Informed consent to participate in this study.
排除标准
- •Pre-existing ILRs or permanent pacemakers that do not allow for continuous monitoring for AF occurrence, or are not MRI-safe.
- •Unable to undergo general anaesthesia for AF ablation.
- •Previous cardiac surgery, such as coronary artery bypass grafting or valvular surgery.
- •Scheduled for elective cardiac surgery, such as coronary artery bypass grafting or valvular surgery.
- •Previous thoracic surgery.
- •Participation in a conflicting study.
- •Potential participants who are mentally incapacitated and cannot consent or comply with follow-up
- •Pregnancy
- •Other cardiac rhythm disorders
结局指标
主要结局
Recurrence of persistent AF by 12 months after ablation
时间窗: 12 months
Mean time to recurrence of persistent AF after ablation
次要结局
- Time to first episode of symptomatic AF after ablation(12 months)
- Time to first episode of any AF after ablation(12 months)
- Total number of AF episodes after AF ablation(12 months)
- Total number of AF episodes lasting greater than 6 minutes after AF ablation(12 months)
- New MRI-detected subclinical cerebral embolic events(3 months)
- Change in AF burden after AF ablation(12 months)
研究者
Neil Sulke
Principal Investigator
Eastbourne General Hospital
研究点 (4)
Loading locations...
相似试验
撤回
不适用
Clinical Outcomes of Persistent Atrial Fibrillation Ablation Using Ablation Index-guided Radiofrequency Catheter Ablation in Patients With Continuous MonitoringPersistent Atrial FibrillationNCT05406310St. Louis University
已完成
不适用
Reducing Recurrence of Symptomatic Atrial Fibrillation After Catheter Ablation by App-based Mental TrainingMeditationParoxysmal Atrial FibrillationPersistent Atrial FibrillationNCT04067427Helios Health Institute GmbH183
撤回
不适用
Serial Hybrid Atrial Fibrillation AblationAtrial FibrillationNCT01582828Medisch Spectrum Twente162
已完成
不适用
ECG-I Targeted Ablation for Persistent AF Not Responding to Pulmonary Vein Isolation Results of a Two Staged Strategy.Atrial FibrillationNCT04633265Barts & The London NHS Trust150
尚未招募
不适用
cliNIcal sCEnarios and Pathophysiology of Atrial FibrillationAtrial FibrillationNCT04320134Policlinico Casilino ASL RMB5,000