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Esthetic, Clinical and Radiographic Outcomes of Immediate and Delayed Implant Placement

Not Applicable
Recruiting
Conditions
Acquired Absence of Single Tooth
Jaw, Edentulous, Partially
Interventions
Procedure: Type 1 implant placement
Procedure: Type 3 implant placement
Registration Number
NCT02814149
Lead Sponsor
Sun Yat-sen University
Brief Summary

The aim of this prospective cohort study is to compare the esthetic, clinical and patient-centered outcomes following immediate and delayed implant placement protocols.

Detailed Description

Patients are divided into two groups: immediate and delayed implant placement. The investigators are asking subjects to take part in a research study of soft tissue and bone healing around dental implants following tooth extraction. The investigators want to compare how the gums and the bone changes shape with healing in two different scenarios.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
40
Inclusion Criteria
  • At least 18 years old and able to understand an informed consent
  • Adequate oral hygiene to allow for implant therapy consistent with standards of care.
  • Missing a single tooth in the maxillary anterior region
  • Presence of adjacent natural teeth
Exclusion Criteria
  • Poor oral hygiene
  • Severe parafunctional habits, for example, bruxing and clenching
  • Presence of clinically active periodontal disease as expressed by probing pocket depths≥4 mm in combination with bleeding on probing.
  • Conditions that might lead to a possibly lowered regenerative capacity of the bone, for example, osteoporosis and Paget's disease
  • Pregnant or expecting to be pregnant
  • History of drug and alcohol abuse
  • History of systemic diseases that would contraindicate oral surgical treatment, for example, uncontrolled diabetes (defined as HBA1c level >7%)
  • Radiotherapy in the head and neck area,
  • On certain medications like bisphosphonates or steroids currently or within the past three months
  • Absence of adjacent teeth
  • Unwillingness to return for the follow-up examination
  • Smokers (more than 20 cigarettes per day). Subjects smoking <20 cigarettes per day were requested to stop smoking before and after surgery

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Type 1 implant placementType 1 implant placementImplant is placed immediately following tooth extraction in one surgical procedure
Type 3 implant placementType 3 implant placementImplant is placed in the site which is left to heal for 3 months following tooth extraction
Primary Outcome Measures
NameTimeMethod
Pink and white esthetic scores (PES/WES)Up to 10 years after baseline

Baseline will be at the time of implant placement.Pink and white esthetic scores (PES/WES) will be recorded at 0.5, 1.5, 3.5, 5.5, 7.5, 10.5 years after implant placement.

Radiographic bone volumeUp to 10 years after baseline

Radiographic bone volume be assessed at pre-operation, 0 ,1.5, 1, 1.5, 3.5, 5.5, 7.5, 10.5 years after implant placement.

Secondary Outcome Measures
NameTimeMethod
Implant survivalUp to 10 years after baseline

Implant survival will be assessed at 0.5, 1, 1.5, 3.5, 5.5, 7.5, 10.5 years after implant placement.

Modified bleeding indexUp to 10 years after baseline

Modified bleeding index will be assessed at pre-operation, 0.5, 1, 1.5, 3.5, 5.5, 7.5, 10.5 years after implant placement.

Buccal marginal recessionUp to 10 years after baseline

Buccal marginal recession will be assessed at pre-operation, 0.5, 1, 1.5, 3.5, 5.5, 7.5, 10.5 years after implant placement.

Papilla volumeUp to 10 years after baseline

Papilla volume will be assessed at 0.5, 1, 1.5, 3.5, 5.5, 7.5, 10.5 years after implant placement.

Probing depthUp to 10 years after baseline

Probing depth will be assessed at pre-operation, 0.5, 1, 1.5, 3.5, 5.5, 7.5, 10.5 years after implant placement.

Modified plaque indexUp to 10 years after baseline

Modified plaque index will be assessed at pre-operation, 0.5, 1, 1.5, 3.5, 5.5, 7.5, 10.5 years after implant placement.

Width of keratinized gingivaUp to 10 years after baseline

Width of keratinized gingiva will be assessed at 0.5, 1, 1.5, 3.5, 5.5, 7.5, 10.5 years after implant placement.

Visual analogue scale (VAS)Up to 10 years after baseline

A questionnaire will be recorded at pre-operation, 0.5, 1, 1.5, 3.5, 5.5, 7.5, 10.5 years after implant placement.

Oral health impact profile shortened version (OHIP-I)Up to 10 years after baseline

A questionnaire will be recorded at pre-operation, 0.5, 1, 1.5, 3.5, 5.5, 7.5, 10.5 years after implant placement.

Trial Locations

Locations (1)

Guanghua School of Stomatology Hospital of Stomatology

🇨🇳

Guangzhou, Guangdong, China

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