MedPath

Changes in predictive capacity when adding Ticagrelor and Clopidogrel to an existing allogeneic bloodtransfuion prediction model for cardiac surgery.

Recruiting
Conditions
Coronary heart disease, valvular disease, vascular disease
Registration Number
NL-OMON22097
Lead Sponsor
Department of Cardiac Surgery and Department of Anesthesia Amsterdam UMC
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
3500
Inclusion Criteria

•Patients > 18 years
•Patients receiving on-pump cardiac surgery.
•Patients receiving off-pump cardiac surgery.

Exclusion Criteria

A potential patient who meets any of the following criteria will be excluded from participation in the data collection:
•Cardiac surgery for congenital disorders

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
How accurately does the TRACK model predict allogeneic blood transfusions in the Amsterdam UMC, location AMC, cardiothoracic surgery population?
Secondary Outcome Measures
NameTimeMethod
1.How does the predictive capacity of the TRACK model change when the pre-operative use of P2Y12 inhibitors are added as a predictive factor?<br>2.What is the relationship between pre-operative P2Y12 use and amount and type of blood product transfused<br>3. Is there a difference in the use of transfusion products between Ticagrelor and other P2Y12 inhibitors, such as Clopidogrel?<br>4.Is there a difference in length of hospital stay, and the 30/90 day mortality in patients using Ticagrelor, when compared to other P2Y12 inhibitors such as Clopidogrel?<br>
© Copyright 2025. All Rights Reserved by MedPath