Renal Allograft : Evaluation of Parenchymal Fibrosis by Elastography
Not Applicable
- Conditions
- Renal Transplant
- Interventions
- Device: Magnetic Resonance Elastography, and Supersonic Shear Imaging
- Registration Number
- NCT01234363
- Lead Sponsor
- Hospices Civils de Lyon
- Brief Summary
The purpose of this study is to assess the potential of elastography for noninvasive assessment of fibrosis in renal allograft.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Renal allograft performed less than 3 months before enrolment
Exclusion Criteria
- Contra-indication to magnetic resonance imaging
- Contra-indication to biopsy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Magnetic Resonance Elastography, Supersonic Shear Imaging Magnetic Resonance Elastography, and Supersonic Shear Imaging Magnetic Resonance Elastography and Supersonic Shear Imaging
- Primary Outcome Measures
Name Time Method Correlation between elasticity (as measured by elastography) and (a) Banff score for fibrosis, (b) glomerular filtration rate assessed by creatinine clearance, (c) glomerular filtration rate assessed by insulin clearance 3 months and 12 months after graft
- Secondary Outcome Measures
Name Time Method Correlation between elasticity and arterial resistance index 3 months and 12 months after graft Number of technical failures 12 months Tolerance (assessed by a questionnaire) 3 months and 12 months after graft Evolution of the elasticity of the transplant between 3 and 12 months after graft 3 months and 12 months after graft
Trial Locations
- Locations (1)
Service de Radiologie, Pavillon P Radio, Hôpital Edouard Herriot
🇫🇷Lyon, France