Infectious and Non-infectious Lower Respiratory Diseases in Children With Down Syndrome Followed in Pediatric Pulmonology Consultations in Ile-de-France
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 108
- 试验地点
- 1
- 主要终点
- distribution of lower respiratory tract diseases
研究概览
简要总结
The purpose of this study is to describe infectious and non-infectious lower respiratory tract diseases in children with Down syndrome followed in pediatric pulmonology consultations in Ile de France.
详细描述
Down syndrome is the most common chromosomal abnormality, affecting 600 to 800 births per year. It results in a clinical picture that combines developmental delay, mental deficiency, facial dysmorphism and visceral malformations.
Optimal medical care of Down syndrome patients requires a good knowledge of the different systems affected by the disease, particularly respiratory damage.
Numerous articles have been published describing upper respiratory problems in children with Down syndrome. On the other hand, lower respiratory problems causing significant morbidity and mortality remain underestimated and poorly understood in this population.
The objective of this study is to describe lower respiratory problems in patients with T21, in order to improve their management.
This study will also make it possible to describe more precisely the impact that these attacks have on Down syndrome patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 1 Day 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Child from 0 to 17 years old
- •Carrier of Down syndrome confirmed by karyotype
- •Having had follow-up in a pediatric pulmonology consultation for an infectious or non-infectious lower respiratory tract
- •Not exclusively presenting upper respiratory otorhinolaryngological damage
排除标准
- •Patient under guardianship or curators
- •Adult or holders of parental authority informed of the study and having objected to it
结局指标
主要结局
distribution of lower respiratory tract diseases
时间窗: at day 0
number
次要结局
未报告次要终点