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Phase II study of interim FDG-PET-guided response-adapted therapy in pediatric patients with Hodgkin's lymphoma (HL-14)

Phase 2
Conditions
Hodgkin's lymphoma
Registration Number
JPRN-jRCTs041180174
Lead Sponsor
Koga Yuhki
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
50
Inclusion Criteria

(1) diagnosis of Hodgkin's lymphoma
(2) age under 20 year old at diagnosis
(3) registration at JPLSG CHM-14 study
(4) written informed consent obtained from patient and/or guardians

Exclusion Criteria

(1) Cases where impaired liver, kidney and cardiac functions compromise experimental treatment
(2) Patients who have been treated with anticancer drugs or radiation therapy
(3) Presence of CNS degenerative lesion
(4) Associated intracranial hemorrhage which hinders execution of treatment process
(5) Associated infection which is difficult to control
(6) Pregnant or possibility of pregnancy
(7) Women who are breastfeeding
(8) Past history of malignant neoplasm or multiple primary neoplasms
(9) History of congenital or acquired immune deficiency syndrome
(10) Any other reasons that the attending physician has deemed unsuitable

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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