Effect of Platelet-rich Fibrin on Soft Tissue, Periodontal Pocket Healing and Alveolar Bone Height After Third Molar Surgery
- Conditions
- Platelet-rich Fibrin
- Interventions
- Other: standard third molar surgical removalOther: PRF
- Registration Number
- NCT05866965
- Lead Sponsor
- Lam Cu Phong
- Brief Summary
A Randomized, controlled clinical trial and split-mouth design was performed to assess and compare the effect of platelet-rich fibrin (PRF) on soft tissue healing, periodontal pocket depth and alveolar bone height distal to second molar of the study and control groups after third molar surgical removal.
Sample include of participants who had indication of impacted lower third molars extraction on both sides with symmetrically orientation and same difficult index. All participants had same extraction protocol on both side at Department of Oral surgery, Faculty of Odonto-stomatology, University of Medicine and Pharmacy, Ho Chi Minh City.
Soft tissue healing, periodontal pocket depth and distal bone height were evaluation by an independent investigator.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 26
- Patient over 18 years old.
- Good general health.
- Bilateral lower third molars equivalent in inclination and Pell and Gregory's impaction classification (classification II, III and B, C). The assessment of equivalence between two mandibular third molars was determined on the panoramic radiograph.
- The difference of third molar inclination on both sides not greater than 15 degrees.
- The patient consented to participate in the study after hearing clearly the explanation of purposes and requirements of the study.
- Patients with any systemic disease contraindicated for surgery.
- Presence of acute inflammation or infection at third molar areas.
- Patients refused to participate in the study, did not comply with treatment or did not come to the follow-up examination as required.
- The difference in surgical time between the two groups was more than 10 minutes.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description control standard third molar surgical removal standard third molar surgery following surgical protocol of Department of Oral Surgery, University of Medicine and Pharmacy PRF PRF PRF was applied in third molar socket after removal following surgical protocol of Department of Oral Surgery, University of Medicine and Pharmacy
- Primary Outcome Measures
Name Time Method distal bone resorption 6th postoperative month resorption of alveolar bone height distal to second molar
periodontal pocket depth 6rst postoperative month periodontal pocket depth at distal buccal and distal lingual side of second molar
- Secondary Outcome Measures
Name Time Method soft tissue healing index 7th postoperative day soft tissue healing around third molar socket
Trial Locations
- Locations (1)
University of Medicine and Pharmacy
🇻🇳Ho Chi Minh City, Vietnam